The Houston Texans are AFC South champions for the second straight year.
Andre Johnson had 151 yards receiving and a touchdown, Bryan Braman scored on a blocked punt and Shayne Graham kicked five field goals as the Texans handled the visiting Indianapolis Colts, 29-17, on Sunday.
The Texans (12-2) grabbed their first AFC South title last season after the Colts nosedived without injured quarterback Peyton Manning. Manning is gone and Andrew Luck couldn't do much against Houston's defense. The Colts (9-5) had won three straight and needed a win to clinch a playoff berth a year after going 2-14.
J.J. Watt had three sacks as Houston's defense got back on track a week after a 42-14 loss to New England.
Redskins 38, Browns 21 -- At Cleveland: Rookie Kirk Cousins threw for 329 yards and two touchdowns filling in for injured star Robert Griffin III, leading Washington to its fifth straight win. Cousins connected with Leonard Hankerson for both TDs in his first career start and the Redskins (8-6) barely missed a beat without the talented and multi-dimensional RG3, who sat out with a sprained knee.
49ers 41, Patriots 34 -- At Foxborough, Mass.: San Francisco earned a playoff berth by withstanding a stunning comeback by New England from a 28-point deficit to win in the rain. Michael Crabtree took a short pass from Colin Kaepernick and sped around cornerback Kyle Arrington for a 38-yard touchdown with 6:25 to go, then David Akers made a 28-yard field goal to clinch it.
Kaepernick threw for four touchdowns, two to Crabtree, who had 107 yards receiving. The defense rattled Tom Brady at times, but also yielded 443 yards passing.
Falcons 34, Giants 0 -- At Atlanta: Matt Ryan threw three touchdowns passes and Atlanta handed the Giants their first regular-season shutout since 1996. Julio Jones caught a couple of scoring throws from Ryan, who broke his own franchise records for completions and passing yards in a season. He finished 23 of 28 for 270 yards.
Broncos 34, Ravens 17 -- At Baltimore: Chris Harris returned an interception 98 yards for a momentum-turning touchdown, and Denver won its ninth straight. Peyton Manning threw for 204 yards and a score in his ninth consecutive win against Baltimore, the first with the Broncos (11-3).
Seahawks 50, Bills 17 -- At Toronto: Seattle rookie quarterback Russell Wilson ran for three touchdowns and threw for another in leading the Seahawks to their second straight rout. Wilson scored on runs of 14, 25 and 4 yards and then hit Zach Miller for a 4-yard touchdown in helping the Seahawks score 31 points on their first five possessions.
Cowboys 27, Steelers 24 (OT) -- At Arlington, Texas: Brandon Carr intercepted a pass from Ben Roethlisberger to set up Dan Bailey's 21-yard field goal in overtime. The Cowboys won a Bailey kick on the final play for the second straight week since practice squad linebacker Jerry Brown was killed in a one-car accident that led to manslaughter charges against teammate Josh Brent.
Cardinals 31, Lions 10 -- At Glendale, Ariz.: Greg Toler returned an interception 102 yards for a fourth-quarter touchdown as Arizona ended a nine-game losing streak.
Panthers 31, Chargers 7 -- At San Diego: Mike Tolbert scored twice against his former team and DeAngelo Williams turned a tipped pass from Cam Newton into a 45-yard touchdown reception.
Saints 41, Buccaneers 0 -- At New Orleans: Drew Brees passed for 307 yards and four touchdowns, and New Orleans posted its first shutout since 1995.
Dolphins 24, Jaguars 3 -- At Miami: Ryan Tannehill went 22 for 28 for 220 yards and two scores with no interceptions to help Miami (6-8). The Jaguars (2-12) helped their chances of getting the No. 1 draft pick next April.
Raiders 15, Chiefs 0 -- At Oakland, Calif.: Sebastian Janikowski kicked five field goals and Darren McFadden rushed for 110 yards. There has been little to cheer for this season for the Chiefs, who have lost 10 of 11 games and are tied for the second most losses in franchise history behind a 2-14 mark in 2008.